DOI: https://doi.org/10.36719/2663-4619/114/186-189
Esmer Mirabova
Azerbaijan Medical University
master student
https://orcid.org/0009-0008-7838-5007
esmermirabova@gmail.com
Gulnara Vahabova
Azerbaijan Medical University
PhD in Biology
https://orcid.org/0009-0006-5528-0136
gulnaravahabova@yahoo.com
Cortisol as a Stress Hormone
Abstract
Cortisol, a critical glucocorticoid hormone produced by the adrenal glands, plays a pivotal role in various physiological processes. Its release is finely orchestrated by the suprachiasmatic nucleus, governing the circadian rhythm and activating the intricate hypothalamic–pituitary–adrenal (HPA) axis, a vital neuroendocrine system responsible for stress response and maintaining homeostasis. Disruptions in cortisol regulation due to chronic stress, disease, and aging have profound implications for multiple bodily systems. The presented article provides detailed information about the amount of cortisol in saliva and its effect on cognitive functions
Keywords: cortisol, chronic stress, hypothalamic–pituitary–adrenal (HPA) axis, cognitive impairment, Cushing syndrome, glucocorticoid